Anatomically guided voxel-based partial volume effect correction in brain PET: Impact of MRI segmentation

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Anatomically guided voxel-based partial volume effect correction in brain PET: Impact of MRI segmentation

Partial volume effect is still considered one of the main limitations in brain PET imaging given the limited spatial resolution of current generation PET scanners. The accuracy of anatomically guided partial volume effect correction (PVC) algorithms in brain PET is largely dependent on the performance of MRI segmentation algorithms partitioning the brain into its main classes, namely gray matte...

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PURPOSE Partial volume effect in positron emission tomography (PET) can cause incorrect quantification of radiopharmaceutical uptake in functional imaging. A PET partial volume correction method is presented to attenuate partial volume blurring and to yield voxel-based corrected PET images. METHODS By modeling partial volume effect as a convolution of point spread function of the PET scanner,...

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Comparative assessment of statistical brain MR image segmentation algorithms and their impact on partial volume correction in PET.

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ژورنال

عنوان ژورنال: Computerized Medical Imaging and Graphics

سال: 2012

ISSN: 0895-6111

DOI: 10.1016/j.compmedimag.2012.09.001